Welcome Comparative Effectiveness Research on Cancer in Texas (CERCIT)
CERCIT is a multidisciplinary consortium of investigators at the University of Texas Medical Branch (UTMB), MD Anderson Cancer Center, Rice University and the Texas Department of State Health Services Texas Cancer Registry. CERCIT is funded by the Cancer Prevention Research Institute of Texas (CPRIT).
by UTMB CERCIT, November 2016
The size and diversity of Texas present substantial challenges to the delivery of cancer care throughout the state. The CERCIT Knowledge Translation Core produced the following report and online resources that map population, economic and health care characteristics of diverse geographic areas in Texas that are relevant to the delivery of cancer care.
Read More: Demographic Variations in Texas
by UTMB CERCIT, September 2016
A multi-institutional group, led by James S. Goodwin, MD, has been awarded a second five years of funding for "Comparative Effectiveness Research on Cancer in Texas" (CERCIT). The $6 million grant is from the Cancer Prevention Research Institute of Texas. The CERCIT renewal will build on our analyses of administrative data but expand our methods to better measure individual patient characteristics and include information on patient preferences and patient reported outcomes. Our goal is to generate evidence that will help patients and their physicians make individualized decisions about the best cancer care options for each patient. These choices include screening, treatment and end of life care in cancer.
Read More: CERCIT Renewal
by Rice University Press Release
HOUSTON – (July 25, 2016) – Regions in Texas differ widely in adherence to recommended cancer treatment for elderly patients, according to a study by researchers at Rice University and the University of Texas MD Anderson Cancer Center.
These differences are not due to the availability of treatment specialists or the presence of teaching hospitals, the study found. The absence of consistent explanations for these treatment differences suggests that variations like these are likely to occur elsewhere nationwide.
"Texans are no better off in one city versus another in terms of treatment across a broad range of cancers," said Vivian Ho, the chair in health economics at Rice's Baker Institute for Public Policy and director of the institute's Center for Health and Biosciences, who co-authored the study. "One might have expected Houston residents to receive better treatment because of MD Anderson's presence, but any beneficial effects could be offset by a large number of elderly in Houston not being treated there." The research findings were published in the journal BMC Health Services Research.
Cervical Health Awareness
UTMB's Dr. Ana Rodriguez was interviewed on Univision, January 2016>
January was Cervical Health Awareness Month. UTMB's Dr. Ana Rodriguez was interviewed on Houston Spanish-language television station Univision about the need for women to get screened for cervical cancer and for boys and girls to get vaccinated against the human papillomavirus (HPV) in order to prevent cervical cancer.
by Ana M. Rodriguez, MD, Jan 2016
January is Cervical Health Awareness Month – a time to focus public attention on the need for women across the country to get screened for cervical cancer and for boys and girls to get vaccinated against the human papillomavirus when they are eligible.
Read More: Cervical Cancer Prevention
TMC News, Jan 2016
Despite improvements in diagnoses and treatments, survival rates for women younger than 50 with primary, invasive endometrial cancer are not improving according to a study available online in the Journal of Cancer Research and Clinical Oncology.
Read more: Endometrial Cancer in Women Under 50
2016 CERCIT Publications
|Chavez-MacGregor, M., Clarke, C. A., Lichtensztajn, D. Y., & Giordano, S. H. (2016). Delayed Initiation of Adjuvant Chemotherapy Among Patients With Breast Cancer. JAMA Oncol, 2(3), 322-329. doi:10.1001/jamaoncol.2015.3856||PMID26659132|
|Dimou, F., Sineshaw, H., Parmar, A. D., Tamirisa, N. P., Jemal, A., & Riall, T. S. (2016). Trends in Receipt and Timing of Multimodality Therapy in Early-Stage Pancreatic Cancer. J Gastrointest Surg, 20(1), 93-103; discussion 103. doi:10.1007/s11605-015-2952-7||PMID26503262|
|Elting LS, Xu Y, Chavez-MacGregor M, Giordano SH. Granulocyte growth factor use in elderly patients with non-Hodgkin's lymphoma in the United States: adherence to guidelines and comparative effectiveness. J Supp. Care Cancer, 2016 Jan 3 24(6), 2695-2706.||PMID26797253|
|Esselen, K. M., Cronin, A. M., Bixel, K., Bookman, M. A., Burger, R. A., Cohn, D. E., . . . Wright, A. A. (2016). Use of CA-125 Tests and Computed Tomographic Scans for Surveillance in Ovarian Cancer. JAMA Oncol, 2(11), 1427-1433. doi:10.1001/jamaoncol.2016.1842||PMID27442965|
|Goodwin, J. S., Sheffield, K., Li, S., & Tan, A. (2016). Receipt of Cancer Screening Is a Predictor of Life Expectancy. J Gen Intern Med, 31(11), 1308-1314. doi:10.1007/s11606-016-3787-y||PMID27364834|
|Ho V, Ku-Goto MH, Zhao H, Hoffman E, Smith B, Giordano S. Regional differences in recommended cancer treatment for the elderly. BMC Health Services Research, 2016 16:262 DOI 10.1186/s12913-016-1534-z||Download PDF|
|Huo, J., Giordano, S. H., Smith, B. D., Shaitelman, S. F., & Smith, G. L. (2016). Contemporary Toxicity Profile of Breast Brachytherapy Versus External Beam Radiation After Lumpectomy for Breast Cancer. Int J Radiat Oncol Biol Phys, 94(4), 709-718. doi:10.1016/j.ijrobp.2015.12.013||PMID26972643|
|Huo, J., Smith, B. D., Giordano, S. H., Reece, G. P., & Tina Shih, Y. C. (2016). A comparison of patient-centered economic and clinical outcomes of post-mastectomy breast reconstruction between obese and non-obese patients. Breast, 30, 118-124. doi:10.1016/j.breast.2016.09.004||PMID27697676|
|Kehl, K. L., Shen, C., Litton, J. K., Arun, B., & Giordano, S. H. (2016). Rates of BRCA1/2 mutation testing among young survivors of breast cancer. Breast Cancer Res Treat, 155(1), 165-173. doi:10.1007/s10549-015-3658-y||PMID26706041|
|Lewis, Z. H., Ottenbacher, K. J., Fisher, S. R., Jennings, K., Brown, A. F., Swartz, M. C., & Lyons, E. J. (2016). Testing Activity Monitors' Effect on Health: Study Protocol for a Randomized Controlled Trial Among Older Primary Care Patients. JMIR Res Protoc, 5(2), e59. doi:10.2196/resprot.5454||PMID27129602|
|Lewis, Z. H., Swartz, M. C., & Lyons, E. J. (2016). What's the Point?: A Review of Reward Systems Implemented in Gamification Interventions. Games Health J, 5(2), 93-99. doi:10.1089/g4h.2015.0078||PMID26812253|
|Lin, S. H., Zhang, N., Godby, J., Wang, J., Marsh, G. D., Liao, Z., . . . Giordano, S. H. (2016). Radiation modality use and cardiopulmonary mortality risk in elderly patients with esophageal cancer. Cancer, 122(6), 917-928. doi:10.1002/cncr.29857||PMID26716915|
|Lowenstein, L. M., Richards, V. F., Leal, V. B., Housten, A. J., Bevers, T. B., Cantor, S. B., . . . Volk, R. J. (2016). A brief measure of Smokers' knowledge of lung cancer screening with low-dose computed tomography. Prev Med Rep, 4, 351-356. doi:10.1016/j.pmedr.2016.07.008||PMID27512650|
|Lyons, E. J., Baranowski, T., Basen-Engquist, K. M., Lewis, Z. H., Swartz, M. C., Jennings, K., & Volpi, E. (2016). Testing the effects of narrative and play on physical activity among breast cancer survivors using mobile apps: study protocol for a randomized controlled trial. BMC Cancer, 16, 202. doi:10.1186/s12885-016-2244-y||PMID26960972|
|Mehta, H. B., Parmar, A. D., Adhikari, D., Tamirisa, N. P., Dimou, F., Jupiter, D., & Riall, T. S. (2016). Relative impact of surgeon and hospital volume on operative mortality and complications following pancreatic resection in Medicare patients. J Surg Res, 204(2), 326-334. doi:10.1016/j.jss.2016.05.008||PMID27565068|
|Meyer, L. A., Cronin, A. M., Sun, C. C., Bixel, K., Bookman, M. A., Cristea, M. C., . . . Wright, A. A. (2016). Use and Effectiveness of Neoadjuvant Chemotherapy for Treatment of Ovarian Cancer. J Clin Oncol. doi:10.1200/JCO.2016.68.1239||PMID27601552|
|Nayak, P., Luo, R., Elting, L., Zhao, H., & Suarez-Almazor, M. E. (2016). Impact of Rheumatoid Arthritis on the Mortality of Elderly Patients who Develop Cancer: A Population-Based Study. Arthritis Care Res (Hoboken). doi:10.1002/acr.22997||PMID27483088|
|Nayak, P., Vernon, S. W., Savas, L. S., Basen-Engquist, K., Morgan, R. O., & Elting, L. S. (2016). Functional Impairment and Physical Activity Adherence Among Gynecologic Cancer Survivors: A Population-Based Study. Int J Gynecol Cancer, 26(2), 381-388. doi:10.1097/IGC.0000000000000620||PMID26807568|
|Raber, M., Swartz, M. C., Santa Maria, D., O'Connor, T., Baranowski, T., Li, R., & Chandra, J. (2016). Parental involvement in exercise and diet interventions for childhood cancer survivors: a systematic review. Pediatr Res, 80(3), 338-346. doi:10.1038/pr.2016.84||PMID27064243|
|Sharma, G., Nishi, S. P., Lin, Y. L., Kuo, Y. F., Goodwin, J. S., & Riall, T. S. (2016). Pattern of Imaging after Lung Cancer Resection. 1992-2005. Ann Am Thorac Soc, 13(9), 1559-1567. doi:10.1513/AnnalsATS.201511-768OC||PMID27243464|
|Shirvani, S. M., Jiang, J., Likhacheva, A., Hoffman, K. E., Shaitelman, S. F., Caudle, A., . . . Smith, B. D. (2016). Trends in Local Therapy Utilization and Cost for Early-Stage Breast Cancer in Older Women: Implications for Payment and Policy Reform. Int J Radiat Oncol Biol Phys, 95(2), 605-616. doi:10.1016/j.ijrobp.2016.01.059||PMID27034179|
|Smith, B. D., Jiang, J., Shih, Y. C., Giordano, S. H., Huo, J., Jagsi, R., . . . Shirvani, S. M. (2017). Cost and Complications of Local Therapies for Early-Stage Breast Cancer. J Natl Cancer Inst, 109(1). doi:10.1093/jnci/djw178||PMID27678203|
|Smith, G. L. (2016). Toward Minimizing Overtreatment and Undertreatment of Ductal Carcinoma In Situ in the United States. J Clin Oncol, 34(11), 1172-1174. doi:10.1200/JCO.2015.66.2064||PMID26884563|
|Swartz, M. C., Basen-Engquist, K. M., Markham, C., Lyons, E. J., Cox, M., Chandra, J., . . . Swank, P. R. (2016). Psychometric Analysis of the Three-Factor Eating Questionnaire-R18V2 in Adolescent and Young Adult-Aged Central Nervous System Tumor Survivors. J Adolesc Young Adult Oncol, 5(3), 278-285. doi:10.1089/jayao.2015.0058||PMID27042872|
|Volk, R. J., Linder, S. K., Lopez-Olivo, M. A., Kamath, G. R., Reuland, D. S., Saraykar, S. S., . . . Pignone, M. P. (2016). Patient Decision Aids for Colorectal Cancer Screening: A Systematic Review and Meta-analysis. Am J Prev Med. doi:10.1016/j.amepre.2016.06.022||PMID27593418|
|Williams, S. B., Duan, Z., Chamie, K., Hoffman, K. E., Smith, B. D., Hu, J. C., . . . Giordano, S. H. (2016). Risk of hospitalisation after primary treatment for prostate cancer. BJU Int. doi:10.1111/bju.13647||PMID27561186|
|Zanwar, P., Lin, Y. L., Kuo, Y. F., & Goodwin, J. S. (2016). Downstream tests, treatments, and annual direct payments in older men cared for by primary care providers with high or low prostate-specific antigen screening rates using 100 percent Texas U.S. Medicare public insurance claims data: a retrospective cohort study. BMC Health Serv Res, 16, 17. doi:10.1186/s12913-016-1265-1||PMID26772175|
2015 CERCIT Publications
|Austin MT, Nguyen H, Eberth JM, Chang Y, Heczey A, Hughes DP, Lally KP, & Elting LS. Health disparities are important determinants of outcome for children with solid tumor malignancies. J Pediatr Surg, 2015 Jan 50(1), 161-166.||PMID25598116|
|Chavez-MacGregor M, Niu J, Zhang N, Elting LS, Smith BD, Banchs J, Hortobagyi GN, & Giordano SH. Cardiac Monitoring During Adjuvant Trastuzumab-Based Chemotherapy Among Older Patients With Breast Cancer. J Clin Oncol, 2015 Jul 1 33(19), 2176-2183.||PMID25964256|
|Cooper AB, Parmar AD, Riall TS, Hall BL, Katz MH, Aloia TA, & Pitt HA. Does the use of neoadjuvant therapy for pancreatic adenocarcinoma increase postoperative morbidity and mortality rates? J Gastrointest Surg, 2015 Jan 19(1), 80-86; discussion 86-87.||PMID25091851|
|Gomez DR, Liao KP, Swisher SG, Blumenschein GR, Erasmus JJ, Jr., Buchholz TA, Giordano SH, & Smith BD. Time to treatment as a quality metric in lung cancer: Staging studies, time to treatment, and patient survival. Radiother Oncol, 2015 May 115(2), 257-263.|
|Guadagnolo BA, Liao KP, Giordano SH, Elting LS, & Shih YC. Variation in Intensity and Costs of Care by Payer and Race for Patients Dying of Cancer in Texas: An Analysis of Registry-linked Medicaid, Medicare, and Dually Eligible Claims Data. Med Care, 2015 Jul 53(7), 591-598.||PMID26067883|
|He W, Zhao H, Chan W, Lopez D, Shroff RT, & Giordano SH. Underuse of surgical resection among elderly patients with early-stage pancreatic cancer. Surgery, 2015 Jun 29.||PMID26138347|
|Jagsi R, Jiang J, Momoh AO, Alderman A, Giordano SH, Buchholz TA, Pierce LJ, Kronowitz SJ, & Smith BD. Complications After Mastectomy and Immediate Breast Reconstruction for Breast Cancer: A Claims-based Analysis. Ann Surg, 2015 Apr 14.||PMID25876011|
|Nayak P, Paxton RJ, Holmes H, Thanh Nguyen H, & Elting LS. Racial and ethnic differences in health behaviors among cancer survivors. Am J Prev Med, 2015 Jun 48(6), 729-736.||PMID25998923|
|Riall TS, Adhikari D, Parmar AD, Linder SK, Dimou FM, Crowell W, Tamirisa NP, Townsend CM, Jr., & Goodwin JS. The risk paradox: use of elective cholecystectomy in older patients is independent of their risk of developing complications. J Am Coll Surg, 2015 Apr 220(4), 682-690.||PMID25660731|
|Smith BD. When is good enough really good enough? Defining the role of radiation in low-risk ductal carcinoma in situ. J Clin Oncol, 2015 Mar 1 33(7), 686-691.||PMID25605858|
|Smith GL, Huo J, Giordano SH, Hunt KK, Buchholz TA, & Smith BD. Utilization and Outcomes of Breast Brachytherapy in Younger Women. Int J Radiat Oncol Biol Phys, 2015 Sep 1 93(1), 91-101.||PMID26279027|
|Smith GL, Jiang J, Giordano SH, Meyer LA, & Eifel PJ. Trends in the quality of treatment for patients with intact cervical cancer in the United States, 1999 through 2011. Int J Radiat Oncol Biol Phys, 2015 Jun 1 92(2), 260-267.||PMID25968823|
|Tamirisa NP, Parmar AD, Vargas GM, Mehta HB, Kilbane EM, Hall BL, Pitt HA, & Riall TS. Relative Contributions of Complications and Failure to Rescue on Mortality in Older Patients Undergoing Pancreatectomy. Ann Surg, 2015 Jan 5.||PMID25563871|
|Tamirisa NP, Sheffield KM, Parmar AD, Zimmermann CJ, Adhikari D, Vargas GM, Kuo YF, Goodwin JS, & Riall TS. Surgeon and Facility Variation in the Use of Minimally Invasive Breast Biopsy in Texas. Ann Surg, 2015 Jul 262(1), 171-178.||PMID25185475|
Workshop: Multi-PI Grants
Presented by James S. Goodwin, MD and others at UTMB
CERCIT Workshop August 2014
Fun with Medicare Part D Data presented by James S. Goodwin, MD
CERCIT Workshop August 2014
Shared Decision Making in Cancer Care presented by Nina Tamirisa, MD
CERCIT Workshop June 2014
The use of surgery in the elderly for management of metastatic epidural spinal cord compression presented by Justin E. Bird, MD
CERCIT Workshop June 2014
Population-based assessment of breast reconstruction presented by Ben Smith, MD
Reports and Special Publications
Surveillance Patterns Following Lung Cancer Resection [PDF]: This report describes the current population-based trends in surveillance practices and the use of these modalities in patients with non-small cell lung cancer (NSCLC) following curative resection.
Comparative Effectiveness of MRI vs. Mammography Alone in Patients Undergoing Breast-Conserving Therapy for Breast Cancer [PDF]: This report compares the effectiveness of MRI vs. mammography alone in patients undergoing breast-conserving therapy for breast cancer
Hispanic Cancer Report [PDF]: From A quarterly publication of the Texas Public Health Association (TPHA) Supplement, Fall 2013, A Comprehensive Report on Cancer among Hispanics in Texas.
CERCIT Featured in the Texas Public Health Journal Summer 2013
Using research to keep Texans informed about cancer care – that is at the heart of CERCIT (Comparative Effectiveness Research on Cancer in Texas). A description of this project and selected articles from its four research areas are featured in the Spring 2013 issue of the Texas Public Health Journal, a quarterly publication of the Texas Public Health Association (pages 22-55):
Just how much does cancer cost in Texas? [PDF] Texas Public Health Journal, Vol 63, Issue 4, Fall 2011. Findings are reported in the Cost of Cancer in Texas, 2005 [PDF] published by the Texas Cancer Council.